🔍 ACESO — Knowledge Base

Search 500K+
Clinical Trials Instantly

Named after the Greek goddess of healing, Aceso provides semantic AI search across clinical trials, FDA guidance, EMA guidelines, and scientific literature to inform your protocol development.

500K+Clinical Trials
18+Data Sources
DailyAuto Sync

Connected Data Sources

Access the world's most comprehensive clinical trial and regulatory knowledge

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ClinicalTrials.gov
400K+ Records
US clinical trial registry
📖
PubMed
Clinical Trial Literature
Targeted biomedical research
🇺🇸
FDA Guidance
2,000+ Documents
US regulatory guidance
🇪🇺
EMA Guidelines
500+ Documents
European regulatory
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ICH Guidelines
E6(R3) & More
International standards
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bioRxiv
Preprint Server
Latest research
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ChEMBL
Drug Database
Bioactive molecules
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PubChem
110M+ Compounds
Chemical data

Semantic AI Search

Find exactly what you need with natural language queries

🔍Phase III immunotherapy trials for NSCLC with PD-L1 endpoints
Search
All Sources
ClinicalTrials.gov
PubMed
FDA Guidance
EMA
Last 2 Years
ClinicalTrials.gov
Updated Nov 2025
98% Match
Phase III Study of Pembrolizumab Plus Chemotherapy in First-Line NSCLC
A randomized, double-blind, placebo-controlled study evaluating pembrolizumab in combination with platinum-based chemotherapy as first-line treatment for metastatic non-small cell lung cancer with PD-L1 TPS ≥50%.
OncologyPhase IIIImmunotherapy1,200 patients
PubMed
Oct 2025
94% Match
Meta-Analysis: PD-L1 Expression as Predictive Biomarker in NSCLC Immunotherapy
Systematic review and meta-analysis of 47 trials evaluating PD-L1 expression levels as predictive biomarkers for checkpoint inhibitor response in advanced non-small cell lung cancer patients.
Meta-AnalysisBiomarkers47 Studies
FDA Guidance
Sep 2025
89% Match
Guidance for Industry: Clinical Trial Endpoints for Approval of Immuno-Oncology Drugs
FDA guidance document providing recommendations on clinical trial design, endpoints, and statistical considerations for immuno-oncology drug development programs.
RegulatoryEndpointsFDA

How Aceso Works

AI-powered semantic search that understands clinical context

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Natural Language Query

Ask questions in plain English, just like talking to a colleague

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AI Understanding

Our AI understands clinical terminology and context

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Ranked Results

Get relevance-scored results from 18+ data sources

Powerful Research Tools

Everything you need to research and cite efficiently

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Semantic Search

AI understands clinical context, synonyms, and relationships between concepts.

🎯

Relevance Scoring

Every result is scored for relevance so you see the best matches first.

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Direct Citation

One-click to cite any source directly into your protocol with proper formatting.

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Daily Sync

Data sources are automatically updated every 24 hours with the latest records.

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Save & Organize

Save searches and organize results into collections for your projects.

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Export References

Export citations in BibTeX, RIS, or formatted for Word and EndNote.

Better Together

Aceso doesn't work alone—it's part of a unified ecosystem where every foundation enhances the others

🔍
Aceso
📝

Aglaea Integration

Search and cite without leaving the editor. Insert references directly into your protocol with one click.

  • In-editor search panel
  • One-click citation insert
  • Auto-formatted references
Explore Aglaea
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Hygeia Integration

Every compliance citation links to the full regulatory document. Understand the context behind each rule.

  • Click-through to full guidance
  • Regulation cross-references
  • Amendment history for rules
Explore Hygeia
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Iaso Integration

Attach supporting evidence to amendments. Document why changes were made with linked research.

  • Evidence-based change tracking
  • Research justifications
  • Audit-ready documentation
Explore Iaso

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